Faslodex Dosage

Generic name: fulvestrant
Drug classes: Estrogen receptor antagonists, Hormones / antineoplastics

Medically reviewed by  A Ras MD.

 

Recommended Adult Dosing

Dosage forms:  INJ (pre-filled syringe): 250 mg per 5 mL

Hormone receptor-positive breast CA, advanced

[500 mg IM qmo, starting wk 9]
Start: 500 mg IM x1 on days 1, 15, 29; Info: for postmenopausal pts w/ progressive dz

Hormone receptor-positive HER2-negative breast CA

[advanced dz, monotherapy]
Dose: 500 mg IM qmo, starting wk 9; Start: 500 mg IM x1 on days 1, 15, 29; Info: for postmenopausal pts
[advanced or metastatic dz, combo w/ ribociclib]
Dose: 500 mg IM qmo, starting wk 9; Start: 500 mg IM x1 on days 1, 15, 29; Info: for postmenopausal pts
[advanced or metastatic dz, combo w/ palbociclib or abemaciclib]
Dose: 500 mg IM qmo, starting wk 9; Start: 500 mg IM x1 on days 1, 15, 29; Info: for progressive dz; give w/ LHRH agonist if used for pre/perimenopausal pts

Renal dosing

CrCl >30: no adjustment; CrCl <30: not defined
HD/PD: not defined

Hepatic dosing

Child-Pugh Class B: decr. dose 50%; Child-Pugh Class C: not defined

 

SRC: NLM .