Exparel Dosage
Generic name: bupivacaine liposome
Drug class: Local injectable anesthetics
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: INJ (1.3%): 133 mg per 10 mL, 266 mg per 20 mL
Local analgesia, postop
- [infiltration]
- Dose: up to 266 mg via infiltration x1; Max: 266 mg/dose; Info: see pkg insert for bunionectomy and hemorrhoidectomy dosing examples
Regional analgesia, postop
- [interscalene brachial plexis nerve block]
- Dose: 133 mg perineurally x1
Renal dosing
- renal impairment: not defined, caution advised
- HD/PD: not defined
Hepatic dosing
- [not defined]
- hepatic impairment: caution advised
Recommended Peds Dosing
- Dosage forms: INJ (1.3%): 133 mg per 10 mL, 266 mg per 20 mL
Local analgesia, postop
- [infiltration, 6-17 yo]
- Dose: 4 mg/kg/dose via infiltration x1; Max: 266 mg/dose
Renal dosing
- renal impairment: not defined, caution advised
- HD/PD: not defined
Hepatic dosing
- [not defined]
- hepatic impairment: caution advised
SRC: NLM .