Exkivity Dosage

Generic name: mobocertinib
Dosage form: capsules
Drug class: EGFR inhibitors

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  CAP: 40 mg

Special Note

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments

Non-small cell lung CA, locally advanced or metastatic

[160 mg PO qd]

Info: for pts w/ EGFR exon 20 insertion mutations w/ progressive dz on or after platinum-based chemo; do not open/chew/dissolve cap

Renal dosing

eGFR >30: no adjustment; eGFR <30: not defined

Hepatic dosing

bilirubin 1-3x ULN or AST >ULN: no adjustment; bilirubin >3x ULN and any AST: not defined

SRC: NLM .