Generic name: Hydrogen Peroxide Solution (Seborrheic Keratoses)

Drug class: Topical anti-infectives

Medically reviewed by  A Ras MD.

What is Eskata?

Eskata is a prescription medicine that is used to treat a type of skin growth called seborrheic keratoses.


ESKATA (hydrogen peroxide) topical solution, 40% (w/w) is a clear, colorless solution for topical administration, which contains the active ingredient, hydrogen peroxide.

The chemical name of hydrogen peroxide is dihydrogen dioxide.

The molecular formula of hydrogen peroxide is H2O2 and the molecular weight is 34.01. Hydrogen peroxide is represented by the following structural formula:

Chemical Structure

ESKATA contains 40% (w/w) hydrogen peroxide in an aqueous solution of isopropyl alcohol and water.

 Mechanism of Action

The mechanism of action for ESKATA for the treatment of seborrheic keratosis is unknown.

Before taking Eskata, tell your doctor:

  • If you are allergic to Eskata; any part of this medicine; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
  • If you have broken skin or open wounds where the drug will be used.
  • If there is an infection where Eskata will be used.

This is not a list of all drugs or health problems that interact with this medicine.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Eskata with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Eskata?

  • Tell all of your health care providers that you take Eskata. This includes your doctors, nurses, pharmacists, and dentists.
  • Do not use longer than you have been told by the doctor.
  • This medicine may cause harm if swallowed. If Eskata is swallowed, call a doctor or poison control center right away.
  • Eye problems can happen if Eskata gets in the eyes. This includes very bad eye pain or eye injury like loss of eyesight that may not go back to normal. Tell your doctor right away if Eskata gets in your eyes. You will need to rinse your eyes with water for as long as your doctor tells you to.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Eskata while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

How is Eskata best taken?

Use Eskata as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • This medicine will be given to you by a doctor.

What do I do if I miss a dose?

  • Use a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not use 2 doses at the same time or extra doses.

What are the side effects of Eskata that I need to call my doctor about immediately?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Very bad irritation where Eskata is used.

What are some other side effects of Eskata?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Irritation where Eskata is used.
  • Stinging.
  • Itching.
  • Blisters.
  • Swelling.
  • Redness.
  • Crusting.
  • Scaling.
  • Change in skin color.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at

If overdose is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Eskata?

  • If you need to store Eskata at home, talk with your doctor, nurse, or pharmacist about how to store it.




  • NDC: 71180-001-03
  • 3 Units
    Rx Only
    Store at 20-25°C
  • eskata™
    (hydrogen peroxide) topical solution, 40% (w/w)
  • Single use applicator/0.7 mL. For Topical Use Only.
  • Marketed by
    Aclaris Therapeutics, Inc.
    Malvern, PA 19355
  • US Patent 7,381,427


  • NDC: 71180-002-03
  • 3 Units
    Rx Only
    Store at 20-25°C
  • eskata™
    (hydrogen peroxide) topical solution, 40% (w/w)
  • Single use applicator/1.3 mL. For Topical Use Only.
  • Marketed by
    Aclaris Therapeutics, Inc.
    Malvern, PA 19355
  • US Patent 7,381,427
PRINCIPAL DISPLAY PANEL - 1.3 mL Applicator Carton