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Ery-Tab Dosage

Generic name: erythromycin (oral)
Drug class: Macrolides

Medically reviewed by  A Ras MD.

 

Recommended Adult Dosing

Dosage forms:  DR TAB: 250 mg, 333 mg, 500 mg

Infections, bacterial

[1000 mg/day PO divided q6-12h]
Max: 4 g/day; Info: consider giving on empty stomach; duration varies w/ infection type, pathogen susceptibility

Legionnaires dz

[500-1000 mg PO q6h x10-21 days]
Info: consider giving on empty stomach

Rheumatic fever prophylaxis, secondary

[250 mg PO q12h]
Info: consider giving on empty stomach

Intestinal amebiasis

[1000 mg/day PO divided q6-12h x10-14 days]
Info: not 1st-line agent; consider giving on empty stomach

Infection prophylaxis, colorectal surgery

[dosing protocols may vary]
Dose: 1000 mg PO at 1pm, 2pm, and 11pm the day before 8am surgery; Info: give w/ neomycin sulfate; use w/ mechanical bowel prep

Chancroid

[500 mg PO q8h x7 days]
Info: consider giving on empty stomach

Lymphogranuloma venereum

[500 mg PO q6h x21 days]
Info: not 1st-line agent; consider giving on empty stomach

Granuloma inguinale

[500 mg PO q6h for at least 3wk]
Info: may extend tx if not healed after 3wk; not 1st-line agent; consider giving on empty stomach

Gastroparesis

[250-500 mg PO q8h]
Info: give 30min qac; may require initial IV tx

Pertussis

[500 mg PO q6h x14 days]
Info: consider giving on empty stomach

Renal dosing

[no adjustment]
renal impairment: no adjustment
HD/PD: no adjustment; no supplement

Hepatic dosing

[not defined]
hepatic impairment: caution advised

Recommended Peds Dosing

Dosage forms:  DR TAB: 250 mg, 333 mg, 500 mg

Infections, bacterial

[infants/children]
Dose: 30-50 mg/kg/day PO divided q6-8h; Max: 4 g/day; Info: consider giving on empty stomach; may incr. to 60-100 mg/kg/day PO divided q6-8h if severe infection, max 4 g/day; dose, duration varies w/ infection type, pathogen susceptibility

Pertussis

[*<1 mo]
Dose: 40-50 mg/kg/day PO divided q6h x14 days; Info: not 1st-line agent; consider giving on empty stomach
[1 mo and older]
Dose: 40-50 mg/kg/day PO divided q6h x14 days; Max: 2 g/day; Info: consider giving on empty stomach

Community-acquired pneumonia, atypical

[>3 mo]
Dose: 40 mg/kg/day PO divided q6h x7-10 days; Info: consider giving on empty stomach

Rheumatic fever prophylaxis, secondary

[children]
Dose: 250 mg PO q12h; Info: consider giving on empty stomach

Intestinal amebiasis

[children]
Dose: 30-50 mg/kg/day PO divided q6-8h x10-14 days; Max: 4 g/day; Info: not 1st-line agent; consider giving on empty stomach

Infections, chlamydial

[preadolescents <45 kg]
Dose: 50 mg/kg/day PO divided q6h x14 days; Max: 2 g/day; Info: 1st-line agent; consider giving on empty stomach

Infection prophylaxis, colorectal surgery

[dosing protocols may vary]
Dose: 20 mg/kg/dose PO at 1pm, 2pm, and 11pm the day before 8am surgery; Info: give w/ neomycin sulfate; use w/ mechanical bowel prep

GI dysmotility

[children]
Dose: 10-20 mg/kg/day PO divided q6-8h; Info: use after IV tx; give 30min qac if q8h; give 30min qac and qhs if q6h

Chancroid

[preadolescents >45 kg and adolescents]
Dose: 500 mg PO q8h x7 days; Info: consider giving on empty stomach

Lymphogranuloma venereum

[adolescents]
Dose: 500 mg PO q6h x21 days; Info: not 1st-line agent; consider giving on empty stomach

Granuloma inguinale

[adolescents]
Dose: 500 mg PO q6h for at least 3wk; Info: may extend tx if not healed after 3wk; not 1st-line agent; consider giving on empty stomach

Renal dosing

CrCl <10: decr. usual dose by 25-50% or decr. usual frequency
HD: decr. usual dose by 25-50% or decr. usual frequency; no supplement after dialysis; PD: decr. usual dose by 25-50% or decr. usual frequency; no supplement

Hepatic dosing

[not defined]
hepatic impairment: caution advised

 

SRC: NLM .

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