Ery-Tab Dosage
Generic name: erythromycin (oral)
Drug class: Macrolides
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: DR TAB: 250 mg, 333 mg, 500 mg
Infections, bacterial
- [1000 mg/day PO divided q6-12h]
- Max: 4 g/day; Info: consider giving on empty stomach; duration varies w/ infection type, pathogen susceptibility
Legionnaires dz
- [500-1000 mg PO q6h x10-21 days]
- Info: consider giving on empty stomach
Rheumatic fever prophylaxis, secondary
- [250 mg PO q12h]
- Info: consider giving on empty stomach
Intestinal amebiasis
- [1000 mg/day PO divided q6-12h x10-14 days]
- Info: not 1st-line agent; consider giving on empty stomach
Infection prophylaxis, colorectal surgery
- [dosing protocols may vary]
- Dose: 1000 mg PO at 1pm, 2pm, and 11pm the day before 8am surgery; Info: give w/ neomycin sulfate; use w/ mechanical bowel prep
Chancroid
- [500 mg PO q8h x7 days]
- Info: consider giving on empty stomach
Lymphogranuloma venereum
- [500 mg PO q6h x21 days]
- Info: not 1st-line agent; consider giving on empty stomach
Granuloma inguinale
- [500 mg PO q6h for at least 3wk]
- Info: may extend tx if not healed after 3wk; not 1st-line agent; consider giving on empty stomach
Gastroparesis
- [250-500 mg PO q8h]
- Info: give 30min qac; may require initial IV tx
Pertussis
- [500 mg PO q6h x14 days]
- Info: consider giving on empty stomach
Renal dosing
- [no adjustment]
- renal impairment: no adjustment
- HD/PD: no adjustment; no supplement
Hepatic dosing
- [not defined]
- hepatic impairment: caution advised
Recommended Peds Dosing
- Dosage forms: DR TAB: 250 mg, 333 mg, 500 mg
Infections, bacterial
- [infants/children]
- Dose: 30-50 mg/kg/day PO divided q6-8h; Max: 4 g/day; Info: consider giving on empty stomach; may incr. to 60-100 mg/kg/day PO divided q6-8h if severe infection, max 4 g/day; dose, duration varies w/ infection type, pathogen susceptibility
Pertussis
- [*<1 mo]
- Dose: 40-50 mg/kg/day PO divided q6h x14 days; Info: not 1st-line agent; consider giving on empty stomach
- [1 mo and older]
- Dose: 40-50 mg/kg/day PO divided q6h x14 days; Max: 2 g/day; Info: consider giving on empty stomach
Community-acquired pneumonia, atypical
- [>3 mo]
- Dose: 40 mg/kg/day PO divided q6h x7-10 days; Info: consider giving on empty stomach
Rheumatic fever prophylaxis, secondary
- [children]
- Dose: 250 mg PO q12h; Info: consider giving on empty stomach
Intestinal amebiasis
- [children]
- Dose: 30-50 mg/kg/day PO divided q6-8h x10-14 days; Max: 4 g/day; Info: not 1st-line agent; consider giving on empty stomach
Infections, chlamydial
- [preadolescents <45 kg]
- Dose: 50 mg/kg/day PO divided q6h x14 days; Max: 2 g/day; Info: 1st-line agent; consider giving on empty stomach
Infection prophylaxis, colorectal surgery
- [dosing protocols may vary]
- Dose: 20 mg/kg/dose PO at 1pm, 2pm, and 11pm the day before 8am surgery; Info: give w/ neomycin sulfate; use w/ mechanical bowel prep
GI dysmotility
- [children]
- Dose: 10-20 mg/kg/day PO divided q6-8h; Info: use after IV tx; give 30min qac if q8h; give 30min qac and qhs if q6h
Chancroid
- [preadolescents >45 kg and adolescents]
- Dose: 500 mg PO q8h x7 days; Info: consider giving on empty stomach
Lymphogranuloma venereum
- [adolescents]
- Dose: 500 mg PO q6h x21 days; Info: not 1st-line agent; consider giving on empty stomach
Granuloma inguinale
- [adolescents]
- Dose: 500 mg PO q6h for at least 3wk; Info: may extend tx if not healed after 3wk; not 1st-line agent; consider giving on empty stomach
Renal dosing
- CrCl <10: decr. usual dose by 25-50% or decr. usual frequency
- HD: decr. usual dose by 25-50% or decr. usual frequency; no supplement after dialysis; PD: decr. usual dose by 25-50% or decr. usual frequency; no supplement
Hepatic dosing
- [not defined]
- hepatic impairment: caution advised
SRC: NLM .