Enfuvirtide Dosage

Recommended Adult Dosing

Dosage forms:  INJ: 90 mg per mL

HIV infection, tx-experienced

[90 mg SC bid]

Info: not recommended per DHHS guidelines

Renal dosing

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

Hepatic dosing

[not defined]

Recommended Peds Dosing

Dosage forms:  INJ: 90 mg per mL

HIV infection, tx-experienced

[11-15.5 kg]

Dose: 2 mg/kg/dose SC bid; Max: 90 mg/dose; Alt: 27 mg SC bid; Info: not recommended per DHHS guidelines

[15.6-20 kg]

Dose: 2 mg/kg/dose SC bid; Max: 90 mg/dose; Alt: 36 mg SC bid; Info: not recommended per DHHS guidelines

[20.1-24.5 kg]

Dose: 2 mg/kg/dose SC bid; Max: 90 mg/dose; Alt: 45 mg SC bid; Info: not recommended per DHHS guidelines

[24.6-29 kg]

Dose: 2 mg/kg/dose SC bid; Max: 90 mg/dose; Alt: 54 mg SC bid; Info: not recommended per DHHS guidelines

[29.1-33.5 kg]

Dose: 2 mg/kg/dose SC bid; Max: 90 mg/dose; Alt: 63 mg SC bid; Info: not recommended per DHHS guidelines

[33.6-38 kg]

Dose: 2 mg/kg/dose SC bid; Max: 90 mg/dose; Alt: 72 mg SC bid; Info: not recommended per DHHS guidelines

[38.1-42.5 kg]

Dose: 2 mg/kg/dose SC bid; Max: 90 mg/dose; Alt: 81 mg SC bid; Info: not recommended per DHHS guidelines

[>42.6 kg]

Dose: 90 mg SC bid; Info: not recommended per DHHS guidelines

Renal dosing

[not defined]

renal impairment: consider adult renal dosing for guidance

HD/PD: consider adult renal dosing for guidance

Hepatic dosing

[not defined]