Elelyso Dosage

Generic name: taliglucerase alfa
Drug class: Lysosomal enzymes

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  INJ

Gaucher disease, type 1

[60 units/kg/dose IV q2wk]

Info: adjust dose based on clinical response; if switching from another enzyme replacement tx, start w/ previous enzyme replacement dose 2wk after last admin; consider premed w/ antihistamine, corticosteroid if hypersensitivity rxn

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing

[not defined]

Recommended Peds Dosing

Dosage forms:  INJ

Gaucher disease, type 1

[4 yo and older]

Dose: 60 units/kg/dose IV q2wk; Info: adjust dose based on clinical response; if switching from another enzyme replacement tx, start w/ previous enzyme replacement dose 2wk after last admin; consider premed w/ antihistamine, corticosteroid if hypersensitivity rxn

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing

[not defined]

SRC: NLM .