Elagolix Dosage

Generic name: Elagolix
Brand name: Orilissa,
Dosage form: oral tablet
Drug class: Gonadotropin-releasing hormone antagonists

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  TAB: 150 mg, 200 mg

Endometriosis-assoc. pain, mod-severe

[w/o dyspareunia]
Dose: 150 mg PO qd; Start: after pregnancy excluded or w/in 7 days from onset of menses; Max: 24mo; Info: use shortest effective tx duration
[w/ dyspareunia]
Dose: 200 mg PO bid; Start: after pregnancy excluded or w/in 7 days from onset of menses; Max: 6mo; Info: use shortest effective tx duration

Renal dosing

[no adjustment]
renal impairment: no adjustment
HD/PD: no adjustment; no supplement

Hepatic dosing

Child-Pugh Class B: 150 mg PO qd, max 6mo; Child-Pugh Class C: contraindicated

 

SRC: NLM .