Edex Dosage

Generic name: Alprostadil Injection
Brand names: Caverject, Edex
Drug classes: Impotence agents, Vasodilators

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  INJ (pre-filled syringe): 10 mcg per mL, 20 mcg per mL, 40 mcg per mL

Erectile dysfxn

[vasculogenic/psychogenic/mixed etiology]

Dose: individualize dose intracavernously 3x/wk prn; Start: 2.5 mcg intracavernously x1, then w/in 1h may give 5 mcg x1 if partial response or 7.5 mcg x1 if no response, then after 24h may incr. dose by 5-10 mcg x1 and continue q24h until response; Max: 2 doses/24h during initial titration, then 1 dose/24h; 40 mcg/dose; Info: duration of erection not to exceed 1h; use lowest effective dose

[pure neurogenic etiology]

Dose: individualize dose intracavernously 3x/wk prn; Start: 1.25 mcg intracavernously x1, then w/in 1h may give 2.5 mcg x1, then after 24h may give 5 mcg x1, then may incr. dose by 5 mcg x1 q24h until response; Max: 2 doses/24h during initial titration, then 1 dose/24h; 40 mcg/dose; Info: duration of erection not to exceed 1h; use lowest effective dose

Renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

Hepatic dosing

[not defined]

SRC: NLM .