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Generic name: abobotulinumtoxinA (Dysport)
Brand name: Dysport
Dosage forms: injectable powder for injection (500 units); intramuscular powder for injection (300 units)
Drug class: Skeletal muscle relaxants


What’s abobotulinumtoxinA?


Dysport is used by older adults for the treatment of neck dystonia (abnormal head position ) and neck discomfort).

Dysport can also be utilized to relieve muscle spasms as well as rigidity ( spasticity) of hands, arms feet, legs, and arms in children and adults who are at least 2 years old. Dysport is not a treatment for spasticity due to cerebral palsy.

Dysport can also be utilized to temporarily reduce wrinkles on the face. wrinkles on the face.

Dysport can also be employed for other purposes that are not covered in this guideline.



The botulinum toxin in Dysport may expand to other body parts beyond the area where it was injected. This could cause adverse effects that could be life-threatening.

Consult your physician immediately in the event of an unnatural voice, eyes that are droopy, vision issues or muscle weakness that is severe, difficulty controlling your bladder, or difficulty breathing, speaking, or swallowing.

Points to be considered while taking this medication

  • The units of potency in Dysport are not compatible with other preparations of botulinum toxin 
  • Urgent medical attention is needed in the event of breathing, speech, or swallowing problems
  • The recommended dose and frequency of administration should not exceed
  • Dry eyes can be caused by the treatment of the glabellar line. If symptoms persist, you should consider referring the patient to an eye doctor 
  • The neuromuscular disorder can also cause a worsening of the clinical effects of treatment

Before you start taking this medicine, make sure to consult your doctor

You shouldn’t take this medication if you’re sensitive to botulinum or cow’s milk or an infection in the area that the medicine is injecting. Inform your doctor if you have had any side result after taking botulinum previously.

Speak to your doctor if have ever suffered from:

  • amyotrophic lateral sclerosis 
  • myasthenia gravis;
  • Lambert-Eaton syndrome;
  • a breathing disorder like asthma and emphysema;
  • issues with swallowing
  • Facial muscle weakness of the facial muscles (droopy eyelids and a weak forehead, or trouble lifting your eyebrows);
  • A change in the facial appearance.
  • a seizure disorder;
  • bleeding issues;
  • A heart rhythm disorder, heart failure
  • diabetes;
  • dry eyes after having received Botulinum Toxin in the past;
  • A recent or planned operation (especially for your face) or
  • Other botulinum injections, like Botox, Myobloc, and other botulinum toxin injections like Xeomin.

Dysport is produced of donated human plasma and may be contaminated with viruses or other infectious agents. Plasma donated to the clinic is examined and treated to lower the chance of contamination but there’s the possibility that it may be a carrier of diseases. Consult your physician about any potential risks.

Consult your physician if you are breastfeeding or pregnant.

How do I get Dysport?

Dysport injections should be administered only by a qualified doctor, especially if employed for cosmetic purposes.

The medicine is injected into muscles by a medical professional. Dysport injections should be given at least three months apart. Children shouldn’t receive treatment with Dysport more frequently than once every 12 to 16 weeks.

Dysport injections can be administered to multiple areas at the same time, depending on the issue being treated.

The effects of the Dysport injection are only temporary. Your symptoms can return within three months. After repeated injections, it could take a shorter and shorter time before your symptoms return, particularly when your body develops antibodies against the botulinum toxin.

Do not get botulinum toxin injections with more than one doctor at the same time. If you change your healthcare provider and you switch providers, inform your new doctor how long since the last botulinum injection.

Making use of this medication more frequently than recommended will not improve its effectiveness, and could cause severe adverse negative effects.


Preparation of Dysport Solution for Administration

  • Once the mixture is reconstituted, keep it in the original container in the refrigerator from 2degC to 8 degC (36degF up to 46degF) and make use of it within 24 hours
  • Do not freeze the reconstitution after it has been frozen.
  • Reconstitution guidelines are specific to the 500 and 300 Unit vials
  • Reconstituted Dysport is designed to be used for intramuscular injections only. Following reconstitution, Dysport can be used only for one injection and only for one patient.

Cervical Dystonia 

The initial dose is 500 Units administered intramuscularly, as a dose divided for the muscles affected Re-treatments are scheduled at intervals of 12 to 16 weeks and for longer when necessary, based upon the recurrence of clinical signs using doses ranging from 500 and 1,000 Units in order to maximize the clinical benefit
Re-treatments should not be performed within a period of fewer than 12 weeks.
• Titrate up to 250 Units steps, depending on the response of the patient.

Glabellar Lines

  • Give a total dose of 50 Units, split into five equal portions of 10 units each intramuscularly to the muscles affected to obtain clinical effects
  • Re-treatments should not be administered any more often than once every 3 months.

Spasticity in Adults

  • Pick dose based on the muscles affected, the degree of spasticity, as well as the history of treatment and adverse reactions to botulinum toxin
  • Dosing for upper leg spasticity between 500 and 1000 Units
  • Lower limb spasticity treatment: Up to 1500 units
  • The recommended maximum dose per session of treatment (upper and lower limbs combined) for adults is 1500 units.
  • Re-treatment, based upon the improvement in clinical symptoms shouldn’t be scheduled in intervals less than 12 weeks.

Spasticity in Pediatric Patients

  • Choose the dose that is appropriate for the muscle affected, the severity of spasticity, the treatment history, and adverse reactions for any botulinum toxins.
  • Dosing recommendations for spasticity in the upper limbs 8 units/kg to 16 Units/kg for each limb. The recommended maximum dosage given per treatment session must not be more than 16 Units/kg, or 640 Units, or the number that is less.
  • Dosage recommendations for spasticity of the lower limbs 10 units/kg up to 15 units/kg for each limb. The total dose for each treatment session should not exceed 15 units/kg for unilateral injections into the lower limbs 30 Units/kg for injections in both directions or 1000 Units or the lesser amount.
  • The recommended maximum dose for a therapy session should be 30 units/kg, or 1000 Units, or the lesser amount. Re-treatment, in the event of an improvement in clinical symptoms, is not recommended for intervals less than three months.


What if I miss a dose?

Because botulinum toxin is only a short-term effect and is administered at intervals that are widely spaced and are not a requirement for a dose, a dose that is missed is unlikely to cause harm.

If I consume too much?

Get medical attention immediately or contact toll-free the Poison Help line at 1-800-222-1222.

The symptoms of an overdose may not manifest immediately but may include muscle weakness, difficulty swallowing, or low or weak breathing.

What to be aware of?

Dysport could affect the depth of vision and/or perception. Avoid driving or engaging in hazardous activities until you are aware of the effects this medication will have on your vision and depth perception.

Do not return to normal routines too soon following an injection.

Dysport side effects

Seek medical attention immediately If you notice symptoms that indicate an allergic reaction such as symptoms of hives and breathing problems and feeling as if you could be passing out and swelling of your lips, face tongue, throat, or face.

The botulinum toxins in Dysport may extend to other body areas beyond the injection site. It has resulted in dangerous life-threatening side effects for those who receive botulinum toxin injections even for cosmetic reasons.

Contact your doctor immediately If you experience any of these symptoms (up to a few hours or weeks following having an injection):

  • difficulty breathing, speaking, or swallowing difficulties;
  • vocal slur, drooping eyelids;
  • issues with vision;
  • uncommon or severe weakness of the muscles (especially in a body part that was not treated in the area with medication);
  • discomfort or burning sensation in the urinal, burning or pink urine
  • the loss of bladder control or
  • Vision changes eyes pain severe dry or irritated eyes (your eyes could be more sensitive to light).

Common side effects could be:

  • muscles weak, issues with balance
  • headache pain, joint or muscle pain, or pain in your legs or arms;
  • eyesight changes, drooping or sagging eyelids dry or puffy eyes;
  • an allergic reaction in which the medication was instilled (pain and itching, redness and bruising, numbness and swelling, tingling);
  • nausea;
  • cough, fever, sore throat running nose, or stuffy nose;
  • Voice changes dry mouth, difficulty swallowing, or
  • Feeling exhausted.

This isn’t a complete list of all side effects. other side effects could occur. Contact your doctor to seek medical advice regarding adverse effects. You can report any symptoms to FDA via 1-800-FDA-1088.

What other drugs can impact Dysport?

Other medications can also cause some side effects of Dysport which include allergy or cold medicines muscles relaxers, sleeping medications, bronchodilators, urinary medications or bladders as well as irritable bowel medications. Inform your doctor if frequently use any of these drugs.

Discuss with your doctor any other medications you take including:

  • an injected antibiotic– amikacin, gentamicin, kanamycin, neomycin, paromomycin, streptomycin, tobramycin.

This list is not comprehensive. Other drugs can interact with Dysport such as medications that are prescribed and available over the counter, vitamins, and herbal supplements. There are many possible interactions between drugs that are included in this list. Do not begin an entirely new medication without informing your doctor that you’ve taken Dysport before.

More details

Be sure to keep this medication and other medications away from the reach of children. Never let your medications be shared with anyone else and take this medication only in the manner prescribed by your doctor.

Always consult your physician to confirm that the information provided on this page is applicable to your particular situation.

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