Dupilumab Dosage

Generic name: dupilumab
Brand name: Dupixent
Drug class: Interleukin inhibitors

Medically reviewed by  A Ras MD.

 

Recommended Adult Dosing

Dosage forms:  INJ (pen): 200 mg per 1.14 mL, 300 mg per 2 mL; INJ (pre-filled syringe): 100 mg per 0.67 mL, 200 mg per 1.14 mL, 300 mg per 2 mL

Atopic dermatitis, mod-severe

[300 mg SC q2wk]
Start: 600 mg SC divided in 2 sites x1

Mod-severe eosinophilic asthma, adjunct tx

[200 mg SC q2wk]
Start: 400 mg SC divided in 2 sites x1; Alt: start 600 mg SC divided in 2 sites x1, then 300 mg SC q2wk

Mod-severe PO corticosteroid-dependent asthma, adjunct tx

[300 mg SC q2wk]
Start: 600 mg SC divided in 2 sites x1

Mod-severe asthma w/ concurrent mod-severe atopic dermatitis, adjunct tx

[300 mg SC q2wk]
Start: 600 mg SC divided in 2 sites x1

Chronic rhinosinusitis w/ nasal polyposis, adjunct tx

[300 mg SC q2wk]

Eosinophilic esophagitis

[300 mg SC qwk]

Renal dosing

[not defined]
renal impairment: not defined
HD/PD: not defined

Hepatic dosing

[not defined]

 

SRC: NLM .