Diovan HCT Dosage

Generic name: hydrochlorothiazide and valsartan
Drug class: Angiotensin II inhibitors with thiazides

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  TAB: 80 mg/12.5 mg, 160 mg/12.5 mg, 160 mg/25 mg, 320 mg/12.5 mg, 320 mg/25 mg

Hypertension

[initial therapy]

Dose: 1 tab PO qd; Start: 160 mg/12.5 mg PO qd, may incr. dose after 1-2wk; Max: 320 mg/25 mg/day; Info: for use as initial tx if BP control unlikely on single agent

[replacement/add-on therapy]

Dose: 1 tab PO qd; Start: same doses of both components if replacement tx; start combo at lower dose of either valsartan or HCTZ if receiving prior max tolerable dose of that component as monotherapy; may incr. dose after 3-4wk; Max: 320 mg/25 mg/day

Renal dosing

[see below]

CrCl >30: no adjustment; CrCl 10-30: not defined, caution advised; CrCl <10: avoid use; anuria: contraindicated

HD/PD: avoid use

Hepatic dosing

[not defined]

hepatic impairment: caution advised