Dexilant Dosage

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  DR CAP: 30 mg, 60 mg

GERD

[non-erosive, symptomatic]

Dose: 30 mg PO/NG qd x4wk; Info: may open cap, see PPI Administration Alternatives table

[erosive esophagitis, short-term tx]

Dose: 60 mg PO/NG qd for up to 8wk; Info: may open cap, see PPI Administration Alternatives table

[erosive esophagitis, maintenance tx]

Dose: 30 mg PO/NG qd; Info: for maintenance of healed erosive esophagitis and heartburn relief; may open cap, see PPI Administration Alternatives table

Helicobacter pylori infection

[30 mg PO/NG bid x10-14 days]

Info: part of multi-drug regimen, dosing may vary; search H. pylori Tx Regimens for guidelines; may open cap, see PPI Administration Alternatives table

Renal dosing

[see below]

renal impairment: no adjustment

HD/PD: not defined

Hepatic dosing

[adjust dose amount]

Child-Pugh Class B: 30 mg qd for erosive esophagitis; Child-Pugh Class C: not defined

 Recommended Peds Dosing

Dosage forms:  DR CAP: 30 mg, 60 mg

GERD

[non-erosive symptomatic, 12 yo and older]

Dose: 30 mg PO/NG qd x4wk; Info: may open cap, see PPI Administration Alternatives table

[erosive esophagitis short-term tx, 12 yo and older]

Dose: 60 mg PO/NG qd for up to 8wk; Info: may open cap, see PPI Administration Alternatives table

[erosive esophagitis maintenance tx, 12 yo and older]

Dose: 30 mg PO/NG qd; Info: for maintenance of healed erosive esophagitis and heartburn relief; may open cap, see PPI Administration Alternatives table

Renal dosing

renal impairment: no adjustment

HD/PD: not defined

Hepatic dosing

[adjust dose amount]

Child-Pugh Class B: 30 mg qd for erosive esophagitis; Child-Pugh Class C: not defined

SRC: NLM .