Dexedrine Dosage

Generic name: dextroamphetamine
Brand names: Dexedrine Spansule, ProCentra, Zenzedi
Drug class: CNS stimulants

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  ER CAP: 10 mg, 15 mg

Dosage Forms Discontinued in US

[5 mg ER cap not avail. as brand; see generic]

Narcolepsy

[5-60 mg/day PO divided qd-bid]

Start: 10 mg PO qam, may incr. by 10 mg/day qwk; Max: 60 mg/day; Info: taper dose gradually to D/C if prolonged, high-dose use

ADHD

[5-40 mg/day PO divided qd-bid]

Start: 5 mg PO qam or bid, may incr. by 5 mg/day qwk; Max: 60 mg/day; Info: duration 6-8h; doses >40 mg/day rarely more effective; taper dose gradually to D/C if prolonged, high-dose use

Obesity, short-term tx

[5-15 mg PO qam]

Max: 30 mg/day; Info: give 30-60min before meals; taper dose gradually to D/C if prolonged, high-dose use

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing

[not defined]

 Recommended Peds Dosing

Dosage forms:  ER CAP: 10 mg, 15 mg

Dosage Forms Discontinued in US

[5 mg ER cap not avail. as brand; see generic]

ADHD

[6 yo and older]

Dose: 5-40 mg/day PO divided qd-bid; Start: 5 mg PO qam or bid, may incr. by 5 mg/day qwk; Max: 60 mg/day; Info: duration 6-8h; doses >40 mg/day rarely more effective; taper dose gradually to D/C if prolonged, high-dose use

Narcolepsy

[6-11 yo]

Dose: 5-60 mg/day PO divided qd-bid; Start: 5 mg PO qam, may incr. by 5 mg/day qwk; Max: 60 mg/day; Info: taper dose gradually to D/C if prolonged, high-dose use

[12 yo and older]

Dose: 5-60 mg/day PO divided qd-bid; Start: 10 mg PO qam, may incr. by 10 mg/day qwk; Max: 60 mg/day; Info: taper dose gradually to D/C if prolonged, high-dose use

Obesity, short-term tx

[12 yo and older]

Dose: 5-15 mg PO qam; Max: 30 mg/day; Info: give 30-60min before meals; taper dose gradually to D/C if prolonged, high-dose use

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing

[not defined]

SRC: NLM .