Cuvposa

Generic name: glycopyrrolate(GLY koe PIE roe late)
Drug class: Anticholinergics / antispasmodics

Medically reviewed by A Ras MD.

What is Cuvposa?

Cuvposa is a prescription medicine that is used to reduce drooling. Cuvposa may be given to you for other reasons.

Description

CUVPOSA is an anticholinergic drug available as an oral solution containing 1 mg glycopyrrolate per 5 mL. The chemical name for glycopyrrolate is pyrrolidinium, 3-[(cyclopentylhydroxyphenylacetyl) oxy]-1,1-dimethyl-,bromide. The chemical structure is:

The empirical formula for CUVPOSA is C19H28BrNO3 and the molecular weight is 398.33. The inactive ingredients in CUVPOSA are: citric acid, glycerin, natural and artificial cherry flavor, methylparaben, propylene glycol, propylparaben, saccharin sodium, sodium citrate, sorbitol solution, and purified water.

Mechanism of Action

Glycopyrrolate is a competitive inhibitor of acetylcholine receptors that are located on certain peripheral tissues, including salivary glands. Glycopyrrolate indirectly reduces the rate of salivation by preventing the stimulation of these receptors.

Before taking Cuvposa, tell your doctor:

If you are allergic to Cuvposa; any part of this medicine; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
If you have any of these health problems: Heart problems due to bleeding, enlarged colon, glaucoma, bowel block, myasthenia gravis, slow-moving GI (gastrointestinal) tract, ulcerative colitis, or trouble passing urine.
If you are taking potassium tablets.

This is not a list of all drugs or health problems that interact with this medicine.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Cuvposa with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Cuvposa?

Tell all of your health care providers that you take Cuvposa. This includes your doctors, nurses, pharmacists, and dentists.
Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how Cuvposa affects you.
Talk with your doctor before you drink alcohol or use other drugs and natural products that slow your actions.
If you have constipation, talk with your doctor. There may be ways to lower this side effect.
Heat stroke has happened in people taking Cuvposa. Be careful in hot weather and during physical activity.
Drink lots of noncaffeine liquids after using Cuvposa unless told to drink less liquid by your doctor.
Bright lights may bother you. Wear sunglasses.
If you are 65 or older, use Cuvposa with care. You could have more side effects.
Use with care in children. Talk with the doctor.
Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Cuvposa while you are pregnant.
Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

How is Cuvposa best taken?

Use Cuvposa as ordered by your doctor. Read all information given to you. Follow all instructions closely.

Keep taking Cuvposa as you have been told by your doctor or other health care provider, even if you feel well.
Take on an empty stomach at least 1 hour before or 2 hours after meals unless your doctor has told you otherwise.
Measure liquid doses carefully. Use the measuring device that comes with Cuvposa. If there is none, ask the pharmacist for a device to measure Cuvposa.

What do I do if I miss a dose?

Take a missed dose as soon as you think about it.
If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
Do not take 2 doses at the same time or extra doses.

What are the side effects of Cuvposa that I need to call my doctor about immediately?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
Not sweating during activities or in warm temperatures.
Trouble passing urine.
A fast heartbeat.
A heartbeat that does not feel normal.
Fast breathing.
Fever.
Larger pupils.
Change in eyesight, eye pain, or very bad eye irritation.
Feeling confused.
Diarrhea.
Bloating.
Constipation.
Swelling of belly.
Belly pain.
Very upset stomach or throwing up.
Not able to get or keep an erection.
Muscle weakness.

What are some other side effects of Cuvposa?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

Dry mouth.
Upset stomach or throwing up.
Stuffy nose.
Dizziness.
Feeling sleepy.
Feeling tired or weak.
Blurred eyesight.
Flushing.
Change in taste.
Headache.
Feeling nervous and excitable.
Not able to sleep.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

If overdose is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Cuvposa?

Store at room temperature.
Store in a dry place. Do not store in a bathroom.
Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Label

PRINCIPAL DISPLAY PANEL – 473 ML BOTTLE CARTON

NDC: 0259-0501-16
16 fl. oz.
(473 mL)
Cuvposa®
(glycopyrrolate) oral solution
1 mg/5 mL
(0.2 mg/mL)
Rx Only
For Oral Use Only
Manufactured for:
Merz Pharmaceuticals, LLC
Manufactured by:
Mikart, LLC
Atlanta, GA 30318

SRC: NLM .

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