Cresemba Dosage

Generic name: isavuconazonium
Drug class: Azole antifungals

Medically reviewed by  A Ras MD.

 

Recommended Adult Dosing

Dosage forms:  CAP: 186 mg; INJ: various

Aspergillosis, invasive

[372 mg PO/IV q24h]
Start: 372 mg PO/IV q8h x6 doses; Info: begin maint. dose 12-24h after final loading dose; do not open cap; may mix IV powder in 5 mL water and give PO

Mucormycosis, invasive

[372 mg PO/IV q24h]
Start: 372 mg PO/IV q8h x6 doses; Info: begin maint. dose 12-24h after final loading dose; do not open cap; may mix IV powder in 5 mL water and give PO

Renal dosing

[see below]
renal impairment: no adjustment
HD: no adjustment; no supplement; PD: not defined

Hepatic dosing

Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined, monitor closely

 

 

SRC: NLM .