Cozaar Dosage

Generic name: losartan
Drug class: Angiotensin receptor blockers

Medically reviewed by  A Ras MD.

 

Recommended Adult Dosing

Dosage forms:  TAB: 25 mg, 50 mg, 100 mg

Hypertension

[50-100 mg/day PO divided qd-bid]
Start: 50 mg PO qd; Max: 100 mg/day; Info: start 25 mg PO qd if on diuretic; decr. efficacy as monotherapy in Black pts, consider combo tx

Nephropathy

[100 mg PO qd]
Start: 50 mg PO qd; Max: 100 mg/day; Info: for pts w/ type 2 DM and HTN

Stroke prevention

[50-100 mg PO qd]
Start: 50 mg PO qd; Max: 100 mg/day; Info: for pts w/ HTN and LVH; possibly ineffective in Black pts; may give w/ HCTZ

Heart failure

[25-150 mg PO qd]
Start: 25-50 mg PO qd; Max: 150 mg/day

Renal dosing

[see below]
renal impairment: no adjustment
HD/PD: not defined

Hepatic dosing

[adjust dose amount]
hepatic impairment: start 25 mg qd

 Recommended Peds Dosing

Dosage forms:  TAB: 25 mg, 50 mg, 100 mg

Hypertension

[6 yo and older]
Dose: 0.7-1.4 mg/kg/dose PO qd; Start: 0.7 mg/kg/dose PO qd up to 50 mg/day; Max: 1.4 mg/kg/day up to 100 mg/day; Info: see pkg insert for suspension preparation

Aortic dilation, Marfan syndrome

[1 yo and older]
Dose: 1-1.4 mg/kg/dose PO qd; Start: 0.4 mg/kg/dose PO qd; Max: 100 mg/day; Info: see pkg insert for suspension preparation

Renal dosing

[see below]
CrCl >30: no adjustment; CrCl <30: not defined
HD/PD: not defined

Hepatic dosing

[not defined]
hepatic impairment: consider adult hepatic dosing for guidance

 

 

SRC: NLM .