Corifact Dosage

Generic name: factor XIII
Brand names: Corifact, Tretten
Drug class: Miscellaneous coagulation modifiers

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  INJ

Congenital factor XIII deficiency

[individualize dose IV q4wk]
Start: 40 units/kg/dose IV x1; Info: for bleeding prophylaxis; estimate dose q4wk based on most recent trough factor XIII level w/ goal factor XIII trough level 5-20%; if factor XIII trough level <5% incr. dose 5 units/kg, if two factor XIII trough levels >20% or one factor XIII trough level >25% decr. dose 5 units/kg

Renal dosing

[not defined]
renal impairment: not defined
HD/PD: not defined

Hepatic dosing

[not defined]

Recommended Peds Dosing

Dosage forms:  INJ

Congenital factor XIII deficiency

[individualize dose IV q4wk]
Start: 40 units/kg/dose IV x1; Info: for bleeding prophylaxis; estimate dose q4wk based on most recent trough factor XIII level w/ goal factor XIII trough level 5-20%; if factor XIII trough level <5% incr. dose 5 units/kg, if two factor XIII trough levels >20% or one factor XIII trough level >25% decr. dose 5 units/kg

Renal dosing

[not defined]
renal impairment: not defined
HD/PD: not defined

Hepatic dosing

[not defined]

 

 

SRC: NLM .