Copiktra Dosage

Generic name: duvelisib
Drug class: PI3K inhibitors

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  CAP: 15 mg, 25 mg

 Chronic lymphocytic leukemia

[25 mg PO bid on days 1-28 of 28-day cycle]
Info: possible incr. mortality and serious ADR risk being investigated by FDA, weigh risk/benefit of cont. tx; give PCP prophylaxis during tx and cont. after D/C until CD4+ >200 cells/mm^3; consider CMV prophylaxis; do not open cap

Follicular lymphoma, relapsed or refractory

[indication withdrawn in US]
Info: mfr has voluntarily withdrawn this indication

Renal dosing

CrCl >23: no adjustment; CrCl <23: not defined
HD/PD: not defined

Hepatic dosing

[not defined]

 

SRC: NLM .