Conivaptan Dosage

Generic name: conivaptan
Brand name: Vaprisol
Dosage form: intravenous solution (20 mg/100 mL-D5%)
Drug class: Vasopressin antagonists

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  INJ

Hyponatremia, euvolemic

[20 mg IV x1, then 20 mg/24h IV infusion x2-4 days]

Max: 40 mg/day; 4 days

Hyponatremia

[20 mg IV x1, then 20 mg/24h IV infusion x2-4 days]

Max: 40 mg/day; 4 days

Renal dosing

CrCl <30: avoid use; anuria: contraindicated

HD/PD: not defined

Hepatic dosing

[adjust dose amount]

Child-Pugh Class B or C: start 10 mg x1, then 10 mg/24h x2-4 days, may titrate to 20 mg/24h if needed

SRC: NLM .