Cobimetinib Dosage

Generic name: cobimetinib
Brand name: Cotellic
Dosage form: oral tablet (20 mg)
Drug class: Multikinase inhibitors

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  TAB: 20 mg

Melanoma, unresectable or metastatic

[60 mg PO qd on days 1-21 of 28-day cycle]

Info: for pts w/ BRAF V600E or V600K mutation; use w/ vemurafenib w/ or w/o atezolizumab

Renal dosing

[see below]

CrCl >30: no adjustment; CrCl <30: not defined

HD/PD: not defined

Hepatic dosing

[no adjustment]

SRC: NLM .