Cerezyme Dosage

Generic name: imiglucerase
Drug class: Lysosomal enzymes

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  INJ

Gaucher disease

[2.5 units/kg/dose IV 3x/wk up to 60 units/kg/dose IV q2wk]

Info: individualize dose, frequency based on dz severity, clinical response; if switching from another enzyme replacement tx, start w/ previous enzyme replacement dose 2wk after last admin; consider premed w/ antihistamine, corticosteroid if hypersensitivity rxn

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing

[not defined]

Recommended Peds Dosing

Dosage forms:  INJ

Gaucher disease

[2 yo and older]

Dose: 2.5 units/kg/dose IV 3x/wk up to 60 units/kg/dose IV q2wk; Info: individualize dose, frequency based on dz severity, clinical response; if switching from another enzyme replacement tx, start w/ previous enzyme replacement dose 2wk after last admin; consider premed w/ antihistamine, corticosteroid if hypersensitivity rxn

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing

[not defined]

SRC: NLM .