Celexa Dosage

Generic name: citalopram
Drug class: Selective serotonin reuptake inhibitors

Medically reviewed by  A Ras MD.

 

Recommended Adult Dosing

Dosage forms:  TAB: 10 mg, 20 mg, 40 mg

Major depressive disorder

[20-40 mg PO qd]
Start: 20 mg PO qd, may incr. to 40 mg PO qd after 1wk; Max: 40 mg/day; Info: max 20 mg/day in poor CYP2C19 metabolizers and pts >60 yo; taper dose gradually to D/C

Obsessive-compulsive disorder

[40-60 mg PO qd]
Start: 20 mg PO qd, incr. by 20 mg/day qwk; Max: 60 mg/day; Info: max 20 mg/day in poor CYP2C19 metabolizers and pts >60 yo; taper dose gradually to D/C

Renal dosing

[see below]
mild-moderate impairment: no adjustment; severe impairment: not defined
HD/PD: not defined

Hepatic dosing

[adjust dose amount]
hepatic impairment: max 20 mg/day

Recommended Peds Dosing

 

Dosage forms:  TAB: 10 mg, 20 mg, 40 mg

Major depressive disorder

[7-11 yo]

Dose: 20-40 mg PO qd; Start: 10 mg PO qd, incr. by 5 mg/day q2wk; Max: 40 mg/day; Info: max 20 mg/day in poor CYP2C19 metabolizers; taper dose gradually to D/C

[12 yo and older]

Dose: 20-40 mg PO qd; Start: 20 mg PO qd, may incr. by 10 mg/day q2wk; Max: 40 mg/day; Info: max 20 mg/day in poor CYP2C19 metabolizers; taper dose gradually to D/C

Generalized anxiety disorder

[7-17 yo]

Dose: 10-40 mg PO qd; Start: 5-10 mg PO qd, may incr. dose q2-4wk; Max: 40 mg/day; Info: max 20 mg/day in poor CYP2C19 metabolizers; taper dose gradually to D/C

Obsessive-compulsive disorder

[7-12 yo]

Dose: 10-60 mg PO qd; Start: 2.5-10 mg PO qd, may incr. by 5 mg/day q3wk; Max: 60 mg/day; Info: max 20 mg/day in poor CYP2C19 metabolizers; taper dose gradually to D/C

[13 yo and older]

Dose: 10-60 mg PO qd; Start: 10-20 mg PO qd, may increase. by 10 mg/day q3wk; Max: 60 mg/day; Info: max 20 mg/day in poor CYP2C19 metabolizers; taper dose gradually to D/C

Intermittent explosive disorder

[7-17 yo]

Dose: 10-40 mg PO qd; Start: 10 mg PO qd, may incr. by 10 mg/day qwk; Max: 40 mg/day; Info: max 20 mg/day in poor CYP2C19 metabolizers; taper dose gradually to D/C

Renal dosing

[not defined]

renal impairment: consider adult renal dosing for guidance
HD/PD: not defined

Hepatic dosing

[not defined]

hepatic impairment: consider adult hepatic dosing for guidance

SRC: NLM .