Carbatrol Dosage

Generic name: carbamazepine (oral)
Brand names: Carbatrol, Epitol, EquetroTEGretol, TEGretol XR
Drug class: Dibenzazepine anticonvulsants

Medically reviewed by  A Ras MD.\

 

Recommended Adult Dosing

Dosage forms:  ER CAP: 100 mg, 200 mg, 300 mg

Seizure disorder

[400-600 mg PO bid]
Start: 200 mg PO bid, incr. by 200 mg/day qwk; Max: 1600 mg/day; Info: screen pts of genetically at-risk ancestry (see pkg insert) for HLA-B*1502 allele before initiating tx; adjust dose based on tx response and serum levels; may open cap, but do not crush/chew contents; taper dose gradually to D/C

Trigeminal neuralgia

[200-400 mg PO bid]
Start: 200 mg PO qd x1 day, may incr. by 200 mg/day; Max: 1200 mg/day; Info: screen pts of genetically at-risk ancestry (see pkg insert) for HLA-B*1502 allele before initiating tx; adjust dose based on tx response and serum levels; may open cap, but do not crush/chew contents; taper dose gradually to D/C

Renal dosing

[adjust dose amount]
CrCl <10: decr. usual dose by 25%
HD: decr. usual dose by 25%, on dialysis days admin. after dialysis; no supplement; PD: decr. usual dose by 25%; no supplement

Hepatic dosing

[not defined]
hepatic impairment: caution advised

Recommended Peds Dosing

Dosage forms:  ER CAP: 100 mg, 200 mg, 300 mg

          Seizure disorder

[<12 yo]
Dose: 200-400 mg PO bid; Max: 35 mg/kg/day up to 1000 mg/day; Info: for pts already receiving >400 mg/day IR form; adjust dose based on tx response and serum levels; may open cap, but do not crush/chew contents; taper dose gradually to D/C
[12-15 yo]
Dose: 400 mg PO bid; Start: 200 mg PO bid, incr. by 200 mg/day qwk; Max: 1000 mg/day; Info: screen pts of genetically at-risk ancestry (see pkg insert) for HLA-B*1502 allele before initiating tx; adjust dose based on tx response and serum levels; may open cap, but do not crush/chew contents; taper dose gradually to D/C
[>15 yo]
Dose: 400-600 mg PO bid; Start: 200 mg PO bid, incr. by 200 mg/day qwk; Max: 1200 mg/day; Info: screen pts of genetically at-risk ancestry (see pkg insert) for HLA-B*1502 allele before initiating tx; adjust dose based on tx response and serum levels; may open cap, but do not crush/chew contents; taper dose gradually to D/C

       Renal dosing

[adjust dose amount]
CrCl <10: decr. usual dose by 25%
HD: decr. usual dose by 25%, on dialysis days admin. after dialysis; no supplement; PD: decr. usual dose by 25%; no supplement

        Hepatic dosing

[not defined]
hepatic impairment: caution advised

 

 

SRC: NLM .