Caprelsa Dosage

Generic name: vandetanib
Drug classes: EGFR inhibitors, Multikinase inhibitors, VEGF/VEGFR inhibitors

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  TAB: 100 mg, 300 mg

Restricted Distribution in US

Medullary thyroid CA, unresectable locally advanced or metastatic

[300 mg PO qd]

Info: for pts w/ symptomatic or progressive dz; do not cut/crush/chew, but may disperse tab in water

Renal dosing

CrCl 30-49: 200 mg PO qd; CrCl <30: avoid use

HD/PD: not defined

Hepatic dosing

Child-Pugh Class B or C: avoid use

SRC: NLM .