Caplacizumab Dosage

Generic name: caplacizumab
Brand name: Cablivi
Dosage form: injectable kit (11 mg)
Drug class: Platelet aggregation inhibitors

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  INJ

Special Note

[formulation clarification]

Info: nonproprietary name = caplacizumab-yhdp

Thrombotic thrombocytopenic purpura, acquired

[11 mg IV x1 at least 15 min prior to 1st plasma exchange, then 11 mg SC qd after daily plasma exchange starting day 1 until 30 days after last daily plasma exchange]

Info: use w/ immunosuppressive therapy; may extend tx for up to 28 additional days if persistent dz; D/C if more than 2 dz recurrences during tx; D/C 7 days before elective surgery, dental procedures, or other invasive interventions

Renal dosing

CrCl >15: no adjustment; CrCl <15: not defined

HD/PD: not defined

Hepatic dosing

[not defined]