Buphenyl Dosage

Generic name: sodium phenylbutyrate
Drug class: Urea cycle disorder agents

Medically reviewed by  A Ras MD.

Adult Dosing

Dosage forms:  TAB: 500 mg; PWDR: 3 g per tsp, 8.6 g per Tbsp

Restricted Distribution in US

Chronic hyperammonemia, urea cycle disorder-assoc.

[9.9-13 g/m^2/day PO divided 3-6x/day]

Info: adjust dose based on plasma ammonia, urinary phenylacetylglutamine, and plasma phenylacetate levels; give w/ food

Renal dosing

renal impairment: not defined, caution advised

HD/PD: not defined

Hepatic dosing

[not defined]

hepatic impairment: caution advised

SRC: NLM .