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Brineura Dosage

Generic name: cerliponase alfa
Drug class: Lysosomal enzymes

Medically reviewed by  A Ras MD.

Peds Dosing

Dosage forms:  INJ

Late infantile neuronal ceroid lipofuscinosis type 2

[3 yo and older]
Dose: 300 mg intracerebroventricularly x1 every other week; Start: 5-7 days after intraventricular access device implantation; Info: premed w/ antihistamines w/ or without antipyretics or corticosteroids 30-60 min prior to infusion; give intracerebroventricular electrolytes immediately after infusion

Renal dosing

[not defined]
renal impairment: not defined
HD/PD: not defined

Hepatic dosing

[not defined]



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