Braftovi Dosage

Generic name: encorafenib
Drug class: Multikinase inhibitors

Medically reviewed by  A Ras MD.

Adult Dosing

Dosage forms:  CAP: 75 mg

Special Note

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments

Melanoma, unresectable or metastatic

[450 mg PO qd]

Info: for pts w/ BRAF V600E or V600K mutation; use w/ binimetinib; decr. dose to max 300 mg PO qd if binimetinib withheld

Colorectal CA, metastatic

[300 mg PO qd]

Info: for pts w/ BRAF V600E mutation; use w/ cetuximab

Renal dosing

CrCl >30: no adjustment; CrCl <30: not defined

HD/PD: not defined

Hepatic dosing

Child-Pugh Class A: no adjustment; Child-Pugh Class B or C: not defined

SRC: NLM .