Boniva Dosage

Generic name: ibandronate (oral/injection)
Drug class: Bisphosphonates

Medically reviewed by  A Ras MD.

Adult Dosing

Dosage forms:  TAB: 150 mg; INJ: various

Osteoporosis prevention, postmenopausal

[150 mg PO qmo]

Info: give w/ water 60min before first food/drink/med, avoid lying down x60min; calcium and vitamin D supplementation recommended if inadequate dietary intake; avoid invasive dental procedure; periodically reassess need for tx; consider D/C after 3-5y in low-risk pts

Osteoporosis tx, postmenopausal

[PO route]

Dose: 150 mg PO qmo; Info: give w/ water 60min before first food/drink/med, avoid lying down x60min; calcium and vitamin D supplementation recommended if inadequate dietary intake; avoid invasive dental procedure; reassess need for tx in 3-5y; may consider drug holiday if stable after tx x5y (low-mod risk pt); optimal holiday duration up to 5y; if drug holiday initiated, reassess need for tx q2-4y and consider resuming tx in pts w/ fracture or significant BMD loss

[IV route]

Dose: 3 mg IV q3mo; Info: calcium and vitamin D supplementation recommended if inadequate dietary intake; avoid invasive dental procedure; reassess need for tx in 3y; may consider drug holiday if stable after tx x3y (low-mod risk pt); optimal holiday duration up to 5y; if drug holiday initiated, reassess need for tx q2-4y and consider resuming tx in pts w/ fracture or significant BMD loss

Renal dosing

CrCl <30: avoid use

HD/PD: not defined

Hepatic dosing

[no adjustment]

SRC: NLM .