Binimetinib Dosage

Generic name: binimetinib
Brand name: Mektovi
Dosage form: oral tablet (15 mg)
Drug class: Multikinase inhibitors

Medically reviewed by  A Ras MD.

Adult Dosing

Dosage forms:  TAB: 15 mg

Special info

Info: Prior to prescription, please refer to institution protocols and package information for uses and dosing, including toxicity-related dose changes.

Melanoma, unresectable or metastatic

[45 mg PO q12h]

Info: for pts w/ BRAF V600E or V600K mutation; use w/ encorafenib

Renal dosing

renal impairment: no adjustment

HD/PD: not defined

Hepatic dosing

[adjust dose amount]

bilirubin 1.1-1.5x ULN or AST >ULN: no adjustment; bilirubin >1.5x ULN and any AST: 30 mg q12h

SRC: NLM .