BENZACLIN SIDE EFFECTS
- Generic Name: clindamycin and benzoyl peroxide
- Brand Name: BenzaClin
- Drug Class: Acne Agents, Topical Combos
SIDE EFFECTS
During clinical trials, the most frequently reported adverse event in the BenzaClin (clindamycin and benzoyl peroxide) treatment group was dry skin (12%). The Table below lists local adverse events reported by at least 1% of patients in the BenzaClin (clindamycin and benzoyl peroxide) and vehicle groups.
Local Adverse Events – all causalities in > /= 1% of patients
| BenzaClin n = 420 |
Vehicle n = 168 |
|
| Application site reaction | 13 (3%) | 1 ( < 1%) |
| Dry skin | 50 (12%) | 10 (6%) |
| Pruritus | 8 (2%) | 1 ( < 1%) |
| Peeling | 9 (2%) | – |
| Erythema | 6 (1%) | 1 ( < 1%) |
| Sunburn | 5 (1%) | – |
The actual incidence of dry skin might have been greater were it not for the use of a moisturizer in these studies.
Anaphylaxis, as well as allergic reactions leading to hospitalization, have been reported during post-marketing use of clindamycin/benzoyl peroxide products. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.
SRC: NLM .