Benlysta Dosage

Generic name: belimumab
Drug class: Selective immunosuppressants

Medically reviewed by  A Ras MD.

Adult Dosing

Dosage forms:  INJ (auto-injector): 200 mg; INJ (pre-filled syringe): 200 mg per mL; INJ (vial): various

SLE

[IV route]

Dose: 10 mg/kg/dose IV q4wk; Start: 10 mg/kg/dose IV q2wk x3 doses

[SC route]

Dose: 200 mg SC qwk; Info: give 1st SC dose 1-4wk after last IV dose when switching to SC

Lupus nephritis

[IV route]

Dose: 10 mg/kg/dose IV q4wk; Start: 10 mg/kg/dose IV q2wk x3 doses; Info: may transition to SC route after at least 2 doses administered IV

[SC route]

Dose: 200 mg SC qwk; Start: 400 mg SC qwk x4 doses; Info: if transitioning from IV route, give 200 mg SC qwk 1-2wk after at least 2 doses administered IV

Renal dosing

CrCl >15: no adjustment; CrCl <15: not defined

HD/PD: not defined

Hepatic dosing

[no adjustment]