Beleodaq Dosage

Generic name: belinostat
Drug class: Histone deacetylase inhibitors

Medically reviewed by  A Ras MD.

 

Adult Dosing

Dosage forms:  INJ

Special Note

[uses, dosing may vary]
Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments

Peripheral T-cell lymphoma, relapsed or refractory

[1000 mg/m^2/dose IV x1 on days 1-5 of 21-day cycle]
Info: decr. dose to 750 mg/m^2/dose if homozygous for UGT1A1*28 allele

Renal dosing

CrCl >39: no adjustment; CrCl <39: not defined
HD/PD: not defined

Hepatic dosing

bilirubin <1.5: no adjustment; bilirubin >1.5: not defined, caution advised

 

SRC: NLM .