Bavencio Dosage
Generic name: avelumab
Drug class: Anti-PD-1 monoclonal antibodies
Medically reviewed by A Ras MD.
Adult Dosing
Dosage forms: INJ
Special Note
- [uses, dosing may vary]
- Info: refer to institution protocols and pkg insert prior to prescribing for uses, premeds, and dosing incl. toxicity-related dose adjustments
Merkel cell carcinoma, metastatic
- [800 mg IV q2wk]
Urothelial carcinoma, locally advanced or metastatic
- [maintenance tx]
- Dose: 800 mg IV q2wk; Info: for pts w/ no disease progression after platinum-based first-line tx
- [relapsed or refractory dz]
- Dose: 800 mg IV q2wk; Info: for pts w/ disease progression during or w/in 12mo of platinum-based tx
Renal cell CA, advanced
- [800 mg IV q2wk]
- Info: use w/ axitinib
Renal dosing
- CrCl >15: no adjustment; CrCl <15: not defined
- HD/PD: not defined
Hepatic dosing
- bilirubin 1-3x ULN or AST >ULN: no adjustment; bilirubin >3x ULN: not defined
SRC: NLM .