Balversa Dosage
Generic name: erdafitinib
Drug class: Multikinase inhibitors
Medically reviewed by A Ras MD. Last updated Sept 9, 2022
Adult Dosing
Dosage forms: TAB: 3 mg, 4 mg, 5 mg
Important info
- Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments
Urothelial carcinoma, locally advanced or metastatic
- [8-9 mg PO qd]
- Start: 8 mg PO qd, incr. dose to 9 mg PO qd at 14-21 days if serum phosphate level <5.5 mg/dL, no ocular disorders, and no grade 2 or greater ADR; Info: for pts w/ susceptible fibroblast growth factor receptor 2 or 3 (FGFR2 or FGFR3) genetic alterations, and w/ progressive dz on or after platinum-containing chemo; restrict phosphate intake to 600-800 mg/day
Renal dosing
- eGFR >30: no adjustment; eGFR <30: not defined
- HD/PD: not defined
Hepatic dosing
- Child-Pugh Class A and B: no adjustment; Child-Pugh Class C: not defined
SRC: NLM .