Jump To



Generical name: Ethinyl estradiol and progesterone 
Name of the brand: Annovera
Classification of drugs: Contraceptives

What is Annovera?


Annovera Vaginal Rings are made from silicone and contain two female hormones which release slowly through your vagina, and later are absorbed into your blood. The vaginal ring is progesterone Acetate and the hormone Ethinylestradiol.

Annovera is a contraceptive used by women as contraception to stop the onset of pregnancy.

A single Annovera vaginal ring can be used again for up to one year.


Annovera is not recommended for use Annovera if your condition is: uncontrolled high blood pressure, heart issues or coronary artery disease diminished blood flow to the brain, chronic diabetes (or health issues due to diabetes) and undiagnosed vaginal bleeding liver disease, liver cancer, and severe headaches, particularly when you are also taking certain hepatitis C medications, or if you are scheduled for major surgery, or if you smoke and over 35 or have ever suffered an attack of the heart, stroke, blood clot or breast cancer, the uterus/cervix or vagina.

It is recommended not to take Annovera if smoking and are over 35 years old.

Do not wear an Annovera vaginal ring when you are pregnant or have recently had a child.

Before taking this medication, you must consult your physician

It is not recommended to make use of Annovera in the event that you are allergic to progesterone or EthinylEstradiol :

  • Uncontrolled high blood pressure that is not controlled (especially when you have damaged blood vessels);
  • heart-related problems (coronary artery disease and heart rhythm disorders, a heart valve problem or the history of stroke, heart attack, or blood clots);
  • decreased blood flow to the brain
  • A higher risk of getting blood clots as a result of heart problems or hereditary blood disorder
  • Diabetes (and you are older than 35 or have had diabetes for longer than twenty years);
  • a health issue related to diabetes (vision issues kidney problems nerve damage, circulation issues);
  • A history of cancer-related to hormones as well as cancers of breast vagina, or uterus/cervix;
  • abnormal vaginal bleeding that has not been examined by a physician;
  • headaches, migraines, or severe headaches that cause vision changes
  • the liver, or cancer of the liver and
  • if you have taken any hepatitis C medication containing ombitasvir/paritaprevir/ritonavir in the past 2 weeks.

You shouldn’t take Annovera if smoking and are over 35 years old. Using this medicine increases the chance of developing stroke, blood clots as well as heart attack particularly when you smoke.

To be sure Annovera is suitable for you, inform your doctor if previously had:

  • heart disease or high blood pressure or if you’re susceptible to blood clots
  • Triglycerides or high cholesterol (a kind of fat that is found in the blood);
  • Jaundice, or liver illness (yellowing of the eyes or skin);
  • kidney disease;
  • gallbladder disease, diabetes;
  • depression, migraine headaches, or a seizure;
  • toxic shock syndrome, or simple vaginal irritation
  • A family history of breast cancer or stroke;
  • a lump in the breast or fibrocystic disease of the breast, and an unusual mammogram or
  • If you’ve had an abortion or miscarriage.

Use an Annovera vaginal band if you are expecting, or if you have had a baby in the past four days. Call your doctor when you do not have your period or believe you could be expecting.

Breastfeeding is not advised during the use of Annovera.

Annovera is not recommended for women who have not yet experienced menstrual cycles or who are no longer experiencing menstrual cycles.

How to take Annovera?

Follow the directions for Annovera as given by your physician. Follow the directions on the label of your prescription and be sure to read the medication guide or instructions sheets.

The Annovera vaginal ring does not hinder pregnancy if worn only in intercourse. You must wear the ring at all times for 3 whole days (21 consecutive days).

In 21 days you can remove the ring. Wait 7 full days before inserting it again. Make sure to stick to the schedule of inserting and taking off the rings.

Do not take the Annovera bandage out of your vagina for more than two hours in the 21-day wear duration.

If a ring gets snagged then wash it using moderate soap and hot water. wipe dry on a dry towel and then insert it.

There is a possibility that you will need to use backup birth controls (condoms or spermicides, but not condoms for females) for seven days consecutively:

  • If the ring was removed from the vagina for longer than two hours in the 21-day wearing period;
  • If the Annovera ring is been removed from the vagina for more than 7 days;
  • If you’ve recently had a baby but you haven’t yet begun having menstrual periods.

There is a possibility of breakthrough bleeding. Inform your doctor if the bleeding persists for more than 7 days. It could also be extremely large.

If you require major surgery or are being placed on bed rest for long periods of time, you may need to cease making use of Annovera for a short period of time. Any surgeon or doctor who treats you should be aware that you’re using the Annovera vaginal band.

Annovera is not able to protect your body from sexually transmitted infections, such as HIV or AIDS. A condom can keep you safe from these infections.

When the ring falls taken out of the vagina clean the ring using a gentle soap, warm water. dry it, and then place it in the storage case supplied. Keep it at room temperature. Be sure to keep it away from sun, heat, and freezing. Follow the instructions provided to clean your Annovera vaginal ring whenever it is not being used.

After you have used an Annovera vaginal ring for one year, remove the vaginal ring you used in the pouch or case it came in, and then throw it away somewhere that pets and children are not able to access it. Don’t flush the ring into a toilet.

If I do not take the dose?

Consult your physician when you’re off the schedule or have difficulties removing vaginal rings.

If I consume too much?

A dose too high of Annovera is not likely to be harmful but could cause nausea or vaginal bleeding.

What to avoid?

Do not leave the ring on the floor for more than three weeks.

Don’t use an oil-based vaginal product like gel, cream, or supp. It is possible to use a vaginal lubricant that is water-based but does not use one with silicone or oil.

Annovera can create dark patches on your face. Avoid tanning beds or sunlight. Protect yourself with protective clothes and apply sunblock (SPF 30 or more) whenever you’re outside.

It is possible that you should not drink grapefruit juice when taking Annovera along with other medications. Talk to your pharmacist or doctor.

Annovera side effects

Take immediate medical attention If you are experiencing symptoms that you are experiencing an allergic reaction. Annovera, such as difficulty breathing; hives, or swelling of your lips, face or tongue.

Contact your doctor immediately If you are suffering from:

  • extremely excessive blood pressure A severe headache unfocused vision, and the sound of a pounding inside your neck or ear;
  • symptoms of an enlargement of blood – sudden weakness or numbness (especially in one part of your body) an intense and sudden headache, difficulty speaking or vision, a stabbing chest pain being exhausted and numbness or pain in either leg;
  • Heart attack signs symptoms of heart attack include chest pressure or pain, pain radiating into your shoulder or jaw nausea, sweating, or vomiting;
  • toxic shock syndrome – rapid body aches, sudden fever as well as skin rash nausea, diarrhea and feeling lightheaded or dizzy;
  • new headaches as well as a shift in intensity or pattern or intensity
  • Jaundice (yellowing of the eyes or skin) or
  • signs of depression mood swings thoughts of the harm you could do to yourself.

The common Annovera adverse effects can include:

  • headache;
  • nausea, vomiting, diarrhea, stomach pain;
  • vaginal itching or discharge
  • menstrual discomfort and breast tenderness
  • vaginal bleeding irregular; or
  • discomfort or burning sensation after you urinate;

This is not a comprehensive list of possible side effects, and other side effects could occur. Contact your doctor for advice regarding medical the effects. You can report any side effects to the FDA at 1-800-FDA-1088.

What other drugs can impact Annovera?

Certain drugs may reduce the effectiveness of birth control and could lead to the birth of a baby. Utilize a barrier type for birth control (a male condom that contains the spermicide but not condoms for females) together with an Annovera vaginal ring when you are also using one of the following medications:

  • aprepitant, bosentan,
  • antifungal medicine;
  • an antiviral medicine that treats the symptoms of hepatitis C or HIV/AIDS
  • Blood pressure medicine;
  • seizure medicine;
  • steroid medicine;
  • thyroid medicine; 
  • tuberculosis medication.

Use the birth control barrier until at the very least 28 consecutive days after the last dose of any of these medications.

Annovera may affect the blood levels for other medications you are taking, which could create side effects or render the medication less efficient. Certain drugs may affect the levels in your blood of progesterone and Ethinyl Estradiol when you combine them together with grapefruit juice.

Discuss with your physician all the medications you currently take as well as any medications you are about to start or stop taking. A variety of drugs can interact with Annovera such as medications that are prescribed and available over the counter as well as vitamins and herbal supplements. There aren’t all interactions mentioned here.

Read Next Article

PHP Code Snippets Powered By : XYZScripts.com